Food for Health
Food for Health
Jiaogulan (Gynostemma pentaphyllum)
Ingredients

Jiaogulan (Gynostemma pentaphyllum)

Explore the available health information, treatment context, and integrative evidence for Jiaogulan (Gynostemma pentaphyllum).

Background
  • Jiaogulan (Gynostemma pentaphyllum) is best known as a traditional Chinese medicine herb. In the Guizhou Province, it is used as an anti-aging herb and many people who drink jiaogulan tea reach very old age. However, no link between jiaogulan tea and living many years has been scientifically proven.
  • Jioagulan has shown some promise for treating cancer. Jiaogulan may also reduce nonalcoholic fatty liver disease, although more studies are needed in both of these areas before a recommendation can be made.
References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

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  • Chen JC, Lu KW, Lee JH, et al. Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3. Anticancer Res 2006;26(6B):4313-4326.
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  • Chou SC, Chen KW, Hwang JS, et al. The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease. Altern Ther Health Med 2006;12(3):34-39.
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  • Han MQ, Liu JX, Gao H. [Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cell]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1995;15(3):147-149.
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  • Hou J, Liu S, Ma Z, et al. Effects of gynostemma pentaphyllum makino on the immunological function of cancer patients. J.Tradit.Chin Med. 1991;11(1):47-52.
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  • Huang TH, Li Y, Razmovski-Naumovski V, et al. Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway. J Biomed Sci 2006;13(4):535-548.
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  • Huang TH, Razmovski-Naumovski V, Salam NK, et al. A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum. Biochem Pharmacol 11-1-2005;70(9):1298-1308.
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  • Liu X, Ye W, Mo Z, et al. Three dammarane-type saponins from Gynostemma pentaphyllum. Planta Med 2005;71(9):880-884.
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  • Takagi J, Imada T, Kikuchi T, et al. A new platelet aggregation factor from Gynostemma pentaphyllum Makino. Chem.Pharm.Bull.(Tokyo) 1985;33(12):5568-5571.
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  • Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1993;13(5):278-80, 261.
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  • Wang C, Zhao X, Mao S, et al. Management of SAH with traditional Chinese medicine in China. Neurol.Res 2006;28(4):436-444.
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  • Wang QF, Chen JC, Hsieh SJ, et al. Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Cancer Lett 9-26-2002;183(2):169-178.
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