Background
- The name agrimonia may have its origin in the Greek word "agremone," which refers to plants that supposedly healed cataracts of the eye. The species name eupatoria relates to Mithradates Eupator, King of Pontus, who is credited with introducing many herbal remedies. The Doctrine of Signatures, developed in Europe in the 16 and 17 Centuries, has listed agrimony as one of the 23 substances with medicinal uses, bearing witness to the extent of its influence at the time.
- Germany's Commission E has approved the use of agrimony (when prepared as a tea) for controlling diarrhea and as a throat gargle to reduce inflammation and relieve sore throat pain (cooled tea).
- Agrimony was one of the most famous vulnerary (healing) herbs with anti-inflammatory and diuretic properties. The tannin content is responsible for many of its medicinal uses. The dried leaves can be used to make tea for drinking or as a throat gargle. Preliminary studies suggest that agrimony may be useful against certain bacterial and viral infections, for tumor growth inhibition, diabetes, and hypertension (high blood pressure). Available clinical trials looked at its use in treating certain skin and gastrointestinal disorders. More human studies are needed to confirm these and other reported uses for agrimony.
References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.
- Chakarski I. Clinical study of a herb combination consisting of Agrimonia eupatoria, Hipericum perforatum, Plantago major, Mentha piperita, Matricaria chamomila for the treatment of patients with chronic gastroduodenitis. Probl Vatr Med 1982;10:78-84.
- Copland A, Nahar L, Tomlinson CT, et al. Antibacterial and free radical scavenging activity of the seeds of Agrimonia eupatoria. Fitoterapia 2003;74(1-2):133-135.
View Abstract - Gao K, Zhou L, Chen J. Experimental study on decoctum Agrimonia pilosa Ledeb-induced apoptosis in HL-60 cells in vitro. Zhong Yao Cai 2000;23(9):561-562.
View Abstract - Gray AM, Flatt PR. Actions of the traditional anti-diabetic plant, Agrimony eupatoria (agrimony): effects on hyperglycaemia, cellular glucose metabolism and insulin secretion. Br J Nutr 1998;80(1):109-114.
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View Abstract - Li Y, Ooi LS, Wang H, et al. Antiviral activities of medicinal herbs traditionally used in southern mainland China. Phytother Res 2004;18(9):718-722.
View Abstract - Miyamoto K, Kishi N, Koshiura R. Antitumor effect of agrimoniin, a tannin of Agrimonia pilosa Ledeb., on transplantable rodent tumors. Jpn J Pharmacol 1987;43(2):187-195.
View Abstract - Park EJ, Oh H, Kang TH, et al. An isocoumarin with hepatoprotective activity in Hep G2 and primary hepatocytes from Agrimonia pilosa. Arch Pharm Res 2004;27(9):944-946.
View Abstract - Patrascu V, Chebac PI. [Favorable therapeutic results in cutaneous porphyria obtained with Agrimonia eupatoria]. Revista De Medicina Interna Neurologie Psihiatrie Neurochirurgie Dermato Venerologie Serie Dermato Venerologia 1984;29(2):153-157.
- Petkov V. Plants and hypotensive, antiatheromatous and coronarodilatating action. Am J Chin Med 1979;7(3):197-236.
View Abstract - Petrovshii GA, Zapadniuk VI, Pasechnik IK, et al. [Cholagogue effect of Bupleurum exaltatum, Agrimonia asiatica, Leontopodium ochroleucum, and Veronica virginica.]. Farmakol Toksikol 1957;20(1):75-77.
View Abstract - Swanston-Flatt SK, Day C, Bailey CJ, et al. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33(8):462-464.
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