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Active hexose correlated compound (AHCC)

Background

  • Active hexose correlated compound (AHCC) is an alpha-glucan-rich dietary supplement extracted from the vegetative part of Basidiomycota mushrooms, such as shiitake (Lentinula edodes).
  • AHCC is thought to stimulate the immune system and to reduce the adverse effects of chemotherapy. AHCC was developed in Japan in 1992 and may also have antioxidant and anticancer activity,prevent the onset of diabetes, and prevent liver injury.

References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

  • Cowawintaweewat, S, Manoromana, S, Sriplung, H, et al. Prognostic improvement of patients with advanced liver cancer after active hexose correlated compound (AHCC) treatment. Asian Pac.J Allergy Immunol 2006;24(1):33-45.
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  • Matsui, Y, Uhara, J, Satoi, S, et al. Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort study. J Hepatol 2002;37(1):78-86.
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  • Spierings, E L, Fujii, H, Sun, B, et al. A Phase I study of the safety of the nutritional supplement, active hexose correlated compound, AHCC, in healthy volunteers. J Nutr.Sci Vitaminol (Tokyo) 2007;53(6):536-539.
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  • Terakawa, N, Matsui, Y, Satoi, S, et al. Immunological effect of active hexose correlated compound (AHCC) in healthy volunteers: a double-blind, placebo-controlled trial. Nutr Cancer 2008;60(5):643-651.
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Disclaimer: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.