Angostura (Galipea officinalis, Angostura trifoliata)

Evidence Ledger: Conditions and Wellness Goals

Evidence by Condition and Wellness Goal

Grades describe the evidence for Angostura (Galipea officinalis, Angostura trifoliata) relative to each listed condition or goal.

Background

Angostura (Galipea officinalis, Angostura trifoliata) is a shrub-like tree that has been studied for its potential antibiotic and cytotoxic (cell killing) activity. The bark is thought to be the main source of its medicinal properties.
Although the angostura tree and AngosturaÂ® aromatic bitters bear the same name, the bitters were named after the city, Angostura, Venezuela, and the proprietary formula is not said to contain angostura.
There is not enough human data available to support the use of angostura for any indication.

References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

Houghton PJ, Woldemariam TZ, Watanabe Y, et al. Activity against Mycobacterium tuberculosis of alkaloid constituents of Angostura bark, Galipea officinalis. Planta Med 1999;65(3):250-254.
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Jacquemond-Collet I, Benoit-Vical F, Valentin A, et al. Antiplasmodial and cytotoxic activity of galipinine and other tetrahydroquinolines from Galipea officinalis. Planta Med 2002;68(1):68-69.
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Jacquemond-Collet I, Bessiere JM, Hannedouche S, et al. Identification of the alkaloids of Galipea officinalis by gas chromatography-mass spectrometry. Phytochem Anal 2001;12(5):312-319.
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Jacquemond-Collet I, Hannedouche S, Fouraste I, et al. Novel quinoline alkaloid from trunk bark of Galipea officinalis. Fitoterapia 2000;71(5):605-606.
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Rakotoson JH, Fabre N, Jacquemond-Collet I, et al. Alkaloids from Galipea officinalis. Planta Med 1998;64(8):762-763.
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