Food for Health
Food for Health
Boxwood (Buxus sempervirens L.)
Ingredients

Boxwood (Buxus sempervirens L.)

Explore the available health information, treatment context, and integrative evidence for Boxwood (Buxus sempervirens L.).

Background
  • Boxwood is an evergreen shrub native to Southern Europe, Western Asia, and Northern Africa.
  • An extract of boxwood, SPV-30 (Arkopharma, France), has been studied for its potential effects in HIV and AIDS; however, available clinical evidence is inconclusive. Product claims for SPV-30 have been controversial.
  • There is currently insufficient available evidence in humans to support the use of boxwood for any medical indication.
References

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

  • Ahmed D, Choudhary MI, Turkoz S, et al. Chemical Constituents of Buxus sempervirens. Planta Med 1988;54(2):173-174.
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  • Ata A, Naz S, Choudhary MI, et al. New triterpenoidal alkaloids from Buxus sempervirens. Z Naturforsch.[C.] 2002;57(1-2):21-28.
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  • Atta-ur-Rahman Au, Ata A, Naz S, et al. New steroidal alkaloids from the roots of buxus sempervirens. J Nat Prod. 1999;62(5):665-669.
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  • Durant J, Chantre PH, Gonzalez G, et al. Efficacy and safety of Buxus sempervirens L. preparations (SPV-30) in HIV-infected asymptomatic patients: a multicentre, randomized, double-blind, placebo-controlled trial. Phytomedicine 1998;5(1):10.
  • Ernst E. [How "ethics arguments" hinder research. With Buxus sempervirens against AIDS?]. Fortschr.Med. 5-20-1998;116(14):6-7.
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  • Gollub MJ, Gerdes H, Bains MS. Radiographic appearances of esophageal stents. Radiographics 1997;17(5):1169-1182.
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  • Kuller K. Happiness reigns in the drug marketplace. GMHC.Treat.Issues 1997;11(4/5):6-8.
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  • Kvaltinova Z, Lukovic L, Machova J, et al. Effect of the steroidal alkaloid buxaminol-E on blood pressure, acetylcholinesterase activity and (3H)quinuclidinyl benzilate binding in cerebral cortex. Pharmacology 1991;43(1):20-25.
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  • Liu JP, Manheimer E, Yang M. Herbal medicines for treating HIV infection and AIDS. Cochrane.Database.Syst.Rev 2005;(3):CD003937.
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  • Loru F, Duval D, Aumelas A, et al. Four steroidal alkaloids from the leaves of Buxus sempervirens. Phytochemistry 2000;54(8):951-957.
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  • Orhan I, Sener B, Choudhary MI, et al. Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. J Ethnopharmacol 2004;91(1):57-60.
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  • Promising results for SPV-30. AIDS Patient.Care 1995;9(5):259.
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  • SPV-30 shows encouraging results. AIDS Patient.Care STDS. 1996;10(3):186-187.
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  • Tominaga T, Guimbertau G, Dubourdieu D. Contribution of benzenemethanethiol to smoky aroma of certain Vitis vinifera L. wines. J Agric.Food Chem 2-26-2003;51(5):1373-1376.
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  • Van Neer FJ, van Ginkel CJ. Allergic contact dermatitis from a boxwood recorder. Contact Dermatitis 1997;36(6):305.
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