- Chicory is native to Europe and temperate regions in Asia; it has been naturalized to the United States. Chicory was cultivated as early as 5,000 years ago by Egyptians as a medicinal plant. Traditionally, chicory juice was used as part of a remedy for headaches. The Romans used chicory as a vegetable or in salads. The root was ground and used as a caffeine-free coffee substitute.
- Chicory is still an important salad vegetable in Europe, especially in France, Belgium, and Holland. In the United States, chicory is also grown as a salad green. Preliminary study has investigated chicory for chronic hepatitis; however, at this time there are no high-quality human trials supporting chicory for any indication.
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Chicory (Cichorium intybus)
Explore the available health information, treatment context, and integrative evidence for Chicory (Cichorium intybus).
Evidence Ledger: Conditions and Wellness Goals
Evidence by Condition and Wellness Goal
Grades describe the evidence for Chicory (Cichorium intybus) relative to each listed condition or goal.
Background
References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.
- Abrams SA, Griffin IJ, Hawthorne KM, et al. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr 2005;82(2):471-476.
View Abstract - Ahmed B, Al Howiriny TA, Siddiqui AB. Antihepatotoxic activity of seeds of Cichorium intybus. J Ethnopharmacol 2003;87(2-3):237-240.
View Abstract - Bischoff TA, Kelley CJ, Karchesy Y, et al. Antimalarial activity of lactucin and lactucopicrin: sesquiterpene lactones isolated from Cichorium intybus L. J Ethnopharmacol 2004;95(2-3):455-457.
View Abstract - Bornet FR, Brouns F, Tashiro Y, et al. Nutritional aspects of short-chain fructooligosaccharides: natural occurrence, chemistry, physiology and health implications. Dig Liver Dis 2002;34 Suppl 2:S111-S120.
View Abstract - Cadot P, Kochuyt AM, van Ree R, et al. Oral allergy syndrome to chicory associated with birch pollen allergy. Int Arch Allergy Immunol 2003;131(1):19-24.
View Abstract - Cavin C, Delannoy M, Malnoe A, et al. Inhibition of the expression and activity of cyclooxygenase-2 by chicory extract. Biochem Biophys Res Commun 2005;327(3):742-749.
View Abstract - Debarbieux-Deleporte M, Delbreil B, Collin T, et al. InsP(3)-mediated calcium release induced by heterologous expression of total chicory Leaf RNA. Biol Cell 2002;94(7-8):545-552.
View Abstract - Delzenne NM, Cani PD, Daubioul C, et al. Impact of inulin and oligofructose on gastrointestinal peptides. Br J Nutr 2005;93 Suppl 1:S157-S161.
View Abstract - Esiyok D, Otles S, Akcicek E. Herbs as a food source in Turkey. Asian Pac J Cancer Prev 2004;5(3):334-339.
View Abstract - Grieshop CM, Flickinger EA, Bruce KJ, et al. Gastrointestinal and immunological responses of senior dogs to chicory and mannan-oligosaccharides. Arch Anim Nutr 2004;58(6):483-493.
View Abstract - Hazra B, Sarkar R, Bhattacharyya S, et al. Tumour inhibitory activity of chicory root extract against Ehrlich ascites carcinoma in mice. Fitoterapia 2002;73(7-8):730-733.
View Abstract - Johannsen FR. Toxicological profile of carboxymethyl inulin. Food Chem Toxicol 2003;41(1):49-59.
View Abstract - Petrovic J, Stanojkovic A, Comic L, et al. Antibacterial activity of Cichorium intybus. Fitoterapia 2004;75(7-8):737-739.
View Abstract - Pool-Zobel BL. Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data. Br J Nutr 2005;93 Suppl 1:S73-S90.
View Abstract - Sakurai N, Iizuka T, Nakayama S, et al. [Vasorelaxant activity of caffeic acid derivatives from Cichorium intybus and Equisetum arvense]. Yakugaku Zasshi 2003;123(7):593-598.
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