Background
- The grapefruit was first described in the 1750s as the "forbidden fruit" of Barbados. It was introduced to Florida in the 1820s. Most grapefruit in the United States is still grown in Florida. Grapefruit juice has been used in folk medicine for the treatment of diabetes as well as to strengthen the immune system. Grapefruit is also added to cosmetics and hair care products as a fragrance.
- Grapefruit has been suggested as a treatment for several conditions, but there is currently insufficient scientific evidence to support the use of grapefruit for any medical disorder. The use of supplemental grapefruit pectin in the prevention of cardiovascular disease and the use of grapefruit seed extract in atopic eczema warrants further scientific investigation before a strong recommendation can be made. There is conflicting research regarding the use of grapefruit for kidney stones.
- Grapefruit juice alters the way some drugs are broken down in the liver. Grapefruit may increase the effects of calcium channel blockers, benzodiazepines, immunosuppressants, and HMG-CoA reductase inhibitors.
References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.
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