Background
- Hoodia is a genus in the plant family Apocynaceae. Although hoodia was introduced to the West in early 2004, the Bushmen of the Kalahari have been eating it for a long time to help ward off hunger and thirst during long trips in the desert.
- Unlike ephedra, hoodia does not work as a stimulant; it acts as an appetite suppressant. The pharmaceutical company, Phytopharm, finds hoodia promising and is currently trying to isolate the appetite-suppressing molecule, P57, to create a patented diet drug in the future. P57 was at one time licensed to Pfizer for development, but was discontinued in 2003.
- There are no available reliable human trials demonstrating efficacy and safety. BBC news reports from 2003 suggested that some samples of hoodia products sold on the Internet might show no evidence of containing actual hoodia.
References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.
- Butler G. Hoodia who? Alive: Canadian Journal of Health & Nutrition 2005;267:90.
- MacLean DB, Luo LG. Increased ATP content/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside. Brain Res 9-10-2004;1020(1-2):1-11.
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