Background
- Jiaogulan (Gynostemma pentaphyllum) is best known as a traditional Chinese medicine herb. In the Guizhou Province, it is used as an anti-aging herb and many people who drink jiaogulan tea reach very old age. However, no link between jiaogulan tea and living many years has been scientifically proven.
- Jioagulan has shown some promise for treating cancer. Jiaogulan may also reduce nonalcoholic fatty liver disease, although more studies are needed in both of these areas before a recommendation can be made.
References
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.
- Chen JC, Chung JG, Chen LD. Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells. Cytobios 1999;100(393):37-48.
View Abstract - Chen JC, Lu KW, Lee JH, et al. Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3. Anticancer Res 2006;26(6B):4313-4326.
View Abstract - Chou SC, Chen KW, Hwang JS, et al. The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease. Altern Ther Health Med 2006;12(3):34-39.
View Abstract - Han MQ, Liu JX, Gao H. [Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cell]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1995;15(3):147-149.
View Abstract - Hou J, Liu S, Ma Z, et al. Effects of gynostemma pentaphyllum makino on the immunological function of cancer patients. J.Tradit.Chin Med. 1991;11(1):47-52.
View Abstract - Huang TH, Li Y, Razmovski-Naumovski V, et al. Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway. J Biomed Sci 2006;13(4):535-548.
View Abstract - Huang TH, Razmovski-Naumovski V, Salam NK, et al. A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum. Biochem Pharmacol 11-1-2005;70(9):1298-1308.
View Abstract - Liu X, Ye W, Mo Z, et al. Three dammarane-type saponins from Gynostemma pentaphyllum. Planta Med 2005;71(9):880-884.
View Abstract - Takagi J, Imada T, Kikuchi T, et al. A new platelet aggregation factor from Gynostemma pentaphyllum Makino. Chem.Pharm.Bull.(Tokyo) 1985;33(12):5568-5571.
View Abstract - Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1993;13(5):278-80, 261.
View Abstract - Wang C, Zhao X, Mao S, et al. Management of SAH with traditional Chinese medicine in China. Neurol.Res 2006;28(4):436-444.
View Abstract - Wang QF, Chen JC, Hsieh SJ, et al. Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Cancer Lett 9-26-2002;183(2):169-178.
View Abstract