Background
- The genus Pedicularis contains several species referred to as louseworts. The common name was derived from the idea that livestock would get lice from eating the plant.
- Pedicularis plants are found mainly in temperate northern hemisphere climates, although some are also found in South America.
- Although animal studies have indicated that certain chemicals found in the plants may have antiproliferative or antioxidant activity, there is insufficient evidence in humans to support the use of Pedicularis species for any indication.
References
- Chen RC, Su JH, Yang SM, et al. Effect of isoverbascoside, a phenylpropanoid glycoside antioxidant, on proliferation and differentiation of human gastric cancer cell. Acta Pharmacol.Sin. 2002;23(11):997-1001.
View Abstract - Jia ZJ, Liu ZM, Wang CZ. Phenylpropanoid and iridoid glycosides from Pedicularis spicata. Phytochemistry 1991;30(11):3745-3747.
View Abstract - Jia ZJ, Liu ZM, Wang CZ. Phenylpropanoid and iridoid glycosides from Pedicularis lasiophrys. Phytochemistry 1992;31(1):263-266.
View Abstract - Kang J, Jia Z. [Chemical constituents of Pedicularis muscicola Maxim]. Zhongguo Zhong.Yao Za Zhi. 1997;22(3):167-2.
View Abstract - Li J, Ge RC, Zheng RL, et al. Antioxidative and chelating activities of phenylpropanoid glycosides from Pedicularis striata. Zhongguo Yao Li Xue.Bao. 1997;18(1):77-80.
View Abstract - Li J, Zheng RL, Liu ZM, et al. Scavenging effects of phenylpropanoid glycosides on superoxide and its antioxidation effect. Zhongguo Yao Li Xue.Bao. 1992;13(5):427-430.
View Abstract - Li J, Zheng Y, Zhou H, et al. Differentiation of human gastric adenocarcinoma cell line MGc80-3 induced by verbascoside. Planta Med 1997;63(6):499-502.
View Abstract - Liao F, Zheng RL, Gao JJ, et al. Retardation of skeletal muscle fatigue by the two phenylpropanoid glycosides: verbascoside and martynoside from Pedicularis plicata maxim. Phytother.Res 1999;13(7):621-623.
View Abstract - Liu ZM, Jia ZJ. Phenylpropanoid and iridoid glycosides from Pedicularis striata. Phytochemistry 1991;30(4):1341-1344.
View Abstract - Rui-Chuan C, Jin-Hua S, Gao-Liang O, et al. Induction of differentiation in human hepatocarcinoma cells by isoverbascoside. Planta Med 2002;68(4):370-372.
View Abstract - Su BN, Zhai JJ, Jia ZJ. New iridoids from Pedicularis artselaeri. J Asian Nat.Prod.Res 1998;1(2):103-109.
View Abstract - Wang CZ, Jia ZJ. Neolignan Glycosides from Pedicularis longiflora. Planta Med 1997;63(3):241-244.
View Abstract - Wang P, Kang J, Zheng R, et al. Scavenging effects of phenylpropanoid glycosides from Pedicularis on superoxide anion and hydroxyl radical by the spin trapping method(95)02255-4. Biochem.Pharmacol. 3-8-1996;51(5):687-691.
View Abstract - Zhang F, Jia Z, Deng Z, et al. In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside. Planta Med 2002;68(2):115-118.
View Abstract - Zheng RL, Wang PF, Li J, et al. Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles. Chem Phys.Lipids 1993;65(2):151-154.
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