Background
- Oscillococcinum® (Anas barbariae hepatis et cordis extractum 200CK HPUS), a patented homeopathic preparation manufactured by a French-based company (Boiron Laboratories), is marketed and widely used for the treatment and prevention of influenza symptoms, including "feeling run down," headache, body aches, chills, and fever. It is made from the heart and liver of wild duck and undergoes multiple dilutions (one part in 100, 200 times in a row, i.e., 200C), after which there are reportedly few to no original duck liver or heart molecules in the final product.
- There is some preliminary evidence in humans suggesting that Oscillococcinum® may shorten the duration of the flu. However, it has not been found to prevent the flu. Despite its popularity and anecdotal reports of effectiveness, there is currently little scientific evidence that Oscillococcinum® is superior to placebo.
- More research is required to determine the efficacy and safety of Oscillococcinum®, especially in young children and pregnant and lactating women.
References
- Attena F, Toscano G, Agozzino E, et al. A randomized trial in the prevention of influenza-like syndromes by homeopathic management. Rev Epidemiol Sante Publique 1995;43(4):380-382. View Abstract
- Casanova P, Gerard R. Results of three years of randomised, multicentre studies on Oscillococcinum/placebo [Bilan de 3 annees d'etudes randomisees multicentriques Oscillococcinum/placebo]. 1992;
- Casanova P. Homeopathy, flu syndrome and double blinding [Homeopathie, syndrome grippal et double insu]. Tonus 1984;(25):26.
- Ernst E. A systematic review of systematic reviews of homeopathy. Br J Clin.Pharmacol 2002;54(6):577-582. View Abstract
- Ferley JP, Zmirou D, D'Adhemar D, et al. A controlled evaluation of a homoeopathic preparation in the treatment of influenza-like syndromes. Br J Clin.Pharmacol 1989;27(3):329-335. View Abstract
- Guo R, Pittler MH, Ernst, E. Complementary medicine for treating or preventing influenza or influenza-like illness. Am.J Med 2007;120(11):923-929. View Abstract
- Jaber, R. Respiratory and allergic diseases: from upper respiratory tract infections to asthma. Prim Care 2002;29(2):231-261. View Abstract
- Linde K, Hondras M, Vickers A, et al. Systematic reviews of complementary therapies - an annotated bibliography. Part 3: homeopathy. BMC Complement Altern Med 2001;1:4. View Abstract
- Nollevaux MA. Clinical study of Mucococcinum 200K as a preventative treatment against flu: a double blind trial versus placebo [Klinische studie van Mucococcinum 200K als preventieve behandeling van griepachtige aandoeningen: een dubbelblinde test tegenover placebo]. 1990;
- Papp R, Schuback G, Beck, E, et al. Oscillococcinum in patients with influenza-like syndromes: a placebo-controlled double-blind evaluation. British Homoeopathic Journal 1998;87:69-76.
- Rottey EE, Verleye GB, Liagre RL. The effects of a homeopathic remedy made of micro-organisms in the prevention of flu. A randomised double-blind trial in GP practices [Het effect van een homeopathische bereiding van micro-organismen bij de preventie van griepsymptomen. Een gerandomiseerd dubbel-blind onderzoek in de huisartspraktijk]. Tijdschrift voor Integrale Geneeskunde 1995;11:54-58.
- van der Wouden JC, Bueving HJ, Poole P. Preventing influenza: an overview of systematic reviews. Respir Med 2005;99(11):1341-1349. View Abstract
- Vickers, A. J. and Smith, C. Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. Cochrane Database Syst Rev 2006;3:CD001957. View Abstract
- Vickers AJ, Smith C. Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. Cochrane Database Syst Rev 2004;(1):CD001957. View Abstract
- Vickers AJ, Smith C. Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. Cochrane Database Syst Rev 2000;(2):CD001957. View Abstract