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Ozone therapy

Background

  • Ozone molecules are composed of three oxygen atoms (O3). Ozone exists high in the earth's atmosphere and absorbs solar radiation.
  • Reports of using ozone for medicinal purposes date to the late 19th century. In modern times, ozone therapists have used different forms of ozone to treat a wide variety of conditions. There has been little scientific study of ozone.

References

  • Basabe E. Ozone therapy a favoring element in the rehabilitation of children with hearing loss. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:275.
  • Bocci VA. A reasonable approach for the treatment of HIV infection in the early phase with ozonotherapy (autohaemotherapy). How inflammatory cytokines may have a therapeutic rule. Mediat Inflammation 1994;3:315-321.
  • Bocci V, Paulesu L. Studies on the biological effects of ozone 1. Induction of interferon gamma on human leucocytes. Haematologica 1990;75(6):510-515.
  • Bocci V. Autohaemotherapy after treatment of blood with ozone. A reappraisal. J Int Med Res 1994;22(3):131-144.
  • Bonetti M, Albertini F, Valdenassi L, et al. [Oxygen-ozone therapy in the treatment of lumbar disk-root compression]. Rivista Neuroradiologia 2001;14(Suppl 3):297-304.
  • Carpendale MT, Griffiss J. Is there a role for medical ozone in the treatment of HIV and associated infections? [abstract]. Proceedings, Eleventh Ozone World Congress, San Francisco, CA, 1993.
  • Carpendale MT, Freeberg JK. Ozone inactivates HIV at noncytotoxic concentrations. Antiviral Res 1991;16(3):281-292.
  • Carpendale MT, Freeberg J, Griffiss JM. Does ozone alleviate AIDS diarrhea? J Clin Gastroenterol 1993;17(2):142-145.
  • Colombo R, D'Angelo F, Vaghi M, et al. [Local treatment of chronic venous ulcers with ozone therapy]. Impegno Ospedaliero, Sezione Scientifica 2002;1-2(31):33.
  • Coppola L, Verrazzo G, Giunta R, et al. Oxygen/ozone therapy and haemorheological parameters in peripheral chronic arterial occlusive disease. Thromb Arterioscler 1992;8:83-90.
  • Dalla Volta G, Troianiello B, Griffini S, et al. [Telethermographic assessment of the efficacy of oxygen-ozone therapy in disc-root compression]. Rivista di Neuroradiologia 2001;14(Suppl 1):103-107.
  • Di Mauro G, Matera D, Di Mauro A, et al. Oxygen-ozone therapy and amitriptyline in disc diseases and herniated intervertebral discs. Rivista di Neuroradiologia 2001;14(Suppl 1):93-95.
  • Fabris G, Tommasini G, Petralia B, et al. [Intraforaminal oxygen-ozone therapy]. Rivista di Neuroradiologia 2001;14(1):61-66.
  • Fillippi A. Ozone in oral surgery--current status and prospects. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:169.
  • Frankum B, Katelaris CH. Ozone therapy in AIDS--truly innocuous? Med J Aust 1993;159(7):493.
  • Franzini M, Bignamini A, Micheletti P, et al. Subcutaneous oxygen-ozone therapy in indurative hypodermatitis and in localised lipodystrophies: a clinical study of efficacy and tolerability. Acta Toxicologica et Therapeutica 1993;14(4):273-288.
  • Gabriel C, Blauhut B, Greul R, Schneeweis B, Roggendorf M. Transmission of hepatitis C by ozone enrichment of autologous blood. Lancet 1996;347(9000):541.
  • Garber GE, Cameron DW, Hawley-Foss N, Greenway D, Shannon ME. The use of ozone-treated blood in the therapy of HIV infection and immune disease: a pilot study of safety and efficacy. AIDS 1991;5(8):981-984.
  • Gjonovich A, Sattin GF, Girotto L, et al. [Resistant lumbar pain: oxygen-ozone therapy compared with other methods]. Rivista di Neuroradiologia 2001;14(Suppl 1):35-38.
  • Gomez M. Ozone therapy in the functional recovery from diseases involving damage to central nervous system cells. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:111.
  • Hernandez F, Menendez S, Wong R. Decrease of blood cholesterol and stimulation of antioxidative response in cardiopathy patients treated with endovenous ozone therapy. Free Radic Biol Med 1995;19(1):115-119.
  • Hooker MH, Gazzard BG. Ozone-treated blood in the treatment of HIV infection. AIDS 1992; 6(1):131.
  • Hsu OK. Ozone may inactivate HIV by reducing p120-CD4 binding affinity, lysing the HIV lipid envelope, and oxidizing the HIV core. International Bio-oxidative Medicine Foundation's 5th Annual Meeting, Dallas, TX, 1994.
  • Kawalski H, Sondej J, Cierpiol-Tracz E. The use of ozonotherapy in the nose correction operations. Acta Chir Plast 1992;34(3):182-184.
  • Kudriavtsev EP, Miroshin SI, Semenov SV, Snigorenko AS, Sidorovich IA. [Ozone therapy of diffuse peritonitis in the early postoperative period]. Khirurgiia (Mosk) 1997;(3):36-41.
  • Marchetti D, La Monaca G. An unexpected death during oxygen-ozone therapy. Am J Forensic Med Pathol 2000;21(2):144-147.
  • Mayer C, Soyka M, Naber D. [Paranoid hallucinatory psychoses in an HIV infected patient on ozone therapy]. Nervenarzt 1991;62(3):194-197.
  • McCabe E. Point of view: a case for ozone therapy. AIDS Patient Care Magazine 1992;6:6.
  • Menendez O. Application of ozone therapy in children with humoral immunity deficiency. Proceedings, Ozone in Medicine--Twelfth World Congress of the International Ozone Association, Lille, France , 271. 1995. Lille, France.
  • Menendez S. Application of ozonized oil in the treatment of infantile giardiasis. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:297.
  • Menendez S. Application of ozonized oil in the treatment of vulvovaginitis preliminary study. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:283.
  • Menendez S, Ferrer L, Perez Z. Ozone therapy and magneto therapy: new methods for the rehabilitation of patients with simple chronic glaucoma. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:99.
  • Ozmen V, Thomas WO, Healy JT, et al. Irrigation of the abdominal cavity in the treatment of experimentally induced microbial peritonitis: efficacy of ozonated saline. Am Surg 1993;59(5):297-303.
  • Paulesu L, Luzzi E, Bocci V. Studies on the biological effects of ozone: 2. Induction of tumor necrosis factor (TNF-alpha) on human leucocytes. Lymphokine Cytokine Res 1991;10(5):409-412.
  • Petralia B, Tommasini G, Lavaroni A, et al. [Back ache treated by ozone therapy]. Rivista di Neuroradiologia 2001;14(Suppl 1):71-73.
  • Riva Sanseverino E. Knee-joint disorders treated by oxygen-ozone therapy. Europa Medicophysica 1989;25(3):163-170.
  • Rodriguez Acosta M, Cespedes Valcarcel A, Tula Suarez L, et al. [Ozone therapy in the management of the optic neuritis epidemic. Benefits or risks]. Revista Cubana de Oftalmologia 1994;7(1/2):39-51.
  • Romeo A, Cirillo F. [Kinesiatrics and oxygen-ozone therapy for lumbosacral disc-root compression]. Rivista Neuroradiologia 2001;14(Suppl 1):47-49.
  • Romero VA, Blanco GR, Menendez CS, et al. [Arteriosclerosis obliterans and ozone therapy. Its administration by different routes]. Angiologia 1993;45(5):177-179.
  • Romero VA, Menendez CS, Gomez MM, et al. [Ozone therapy in the advanced stages of arteriosclerosis obliterans]. Angiologia 1993; 45(4):146-148.
  • Sanseverino ER. Intensive medical and physical treatment of osteoporosis with the aid of oxygen-ozone therapy. Europa Medicophysica 1988;24(4):199-196.
  • Scarchilli A. [Three-year follow-up in the treatment of lumbar pain and sciatica with intradiscal ozone therapy]. Rivista Neuroradiologia 2001;14(1):39-41.
  • Sroczynski J, Antoszewski Z, Matyszczyk B, et al. [Clinical assessment of treatment results for atherosclerotic ischemia of the lower extremities with intraarterial ozone injections]. Pol Tyg Lek 1992;47(42-43):964-966.
  • Tabaracci G. [Ozone therapy by "classic" paraspinal intramuscular injection]. Rivista Neuroradiologia 2001;141(Suppl 1):67-70.
  • Verrazzo G, Coppola L, Luongo C, et al. Hyperbaric oxygen, oxygen-ozone therapy, and rheologic parameters of blood in patients with peripheral occlusive arterial disease. Undersea Hyperb Med 1995;22(1):17-22.
  • Wasser G. Additional therapy of cerebrovascular disorder (acute brain stroke) by ozone therapy. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:91.
  • Wells KH, Latino J, Gavalchin J, Poiesz BJ. Inactivation of human immunodeficiency virus type 1 by ozone in vitro. Blood 1991;78(7):1882-1890.
  • Wolfstadter HD, Sacher J, Hopfenmuller W, et al. Retrospective benefit following individualized naturopathic therapy in HIV-patients at different stages [abstract]. Int Conf AIDS 1992;8(3):147.
  • Wong R. Ozone therapy in ischemic cardiopathy. Proceedings, Twelfth World Congress of the International Ozone Association, Lille, France, 1995:73.
Disclaimer: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.