Background

• Papain is an enzyme (a molecule that speeds up a chemical reaction) found in the latex produced by the fruit of the papaya plant (Carica papaya). The release of this enzyme-rich latex may be part of the plant's defense mechanism and aids in cleaning and sealing the damaged areas of the plant.
• In some parts of Africa, papain is used to treat burn wounds, especially in children, and to stimulate healing. In standard Western medical care, papain-containing agents are commonly used to remove dead tissue from burns and many types of wounds and skin ulcers. Traditionally, papain has also been used as digestive aid. Today, papain remains a popular after-meal supplement.
• Allergic sensitivity to papain may cause symptoms ranging from itchiness to abdominal cramps, diarrhea, and excessive sweating. Papain is used as a meat tenderizer and in processing beer, so symptoms may occur after ingestion of foods seemingly unrelated to papain.

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