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Poppy seed (Papaver somniferum)

Background

  • The opium poppy (Papaver somniferum) is grown for opium, opiates, or poppy seeds, which are used in cooking and baking throughout the world. Morphine, a strong pain killer, is the major alkaloid of the opium poppy. Opium and the drugs derived from opium are addictive and may cause sedation or slowed breathing.
  • All parts of the poppy plant contain morphine and codeine; poppy seeds contain morphine in different amounts and eating foods with poppy seeds may result in false positives for opiates in a drug test. Poppy seed cake, bagels, muffins, and rolls have not been shown to contain enough poppy seed to produce a false positive.
  • Poppy seed itself is not used for any medical condition. Poppy seeds and poppy seed oil have been used in diagnostic procedures and as a carrier and contrast medium.

References

  • Aruna, K. and Sivaramakrishnan, V. M. Plant products as protective agents against cancer. Indian J.Exp.Biol. 1990;28(11):1008-1011.
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  • Bhattacharya, S., Novell, J. R., Winslet, M. C., and Hobbs, K. E. Iodized oil in the treatment of hepatocellular carcinoma. Br.J Surg. 1994;81(11):1563-1571.
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  • Hamuro, M., Nakamura, K., Sakai, Y., Kobashi, S., Iuchi, T., Nanata, M., Nishida, N., Kaminou, T., Matsuoka, T., Takashima, S., and Yamada, R. [Development of non-iodized oily agent in targeting chemoembolization for hepatocellular carcinoma]. Nippon Igaku Hoshasen Gakkai Zasshi 1998;58(11):581-583.
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  • Higashi, S. and Setoguchi, T. Hepatic arterial injection chemotherapy for hepatocellular carcinoma with epirubicin aqueous solution as numerous vesicles in iodinated poppy-seed oil microdroplets: clinical application of water-in-oil-in-water emulsion prepared using a membrane emulsification technique. Adv.Drug Deliv.Rev. 12-6-2000;45(1):57-64.
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  • Huda SN, Grantham-McGregor SM, Tomkins A. Cognitive and motor functions of iodine-deficient but euthyroid children in Bangladesh do not benefit from iodized poppy seed oil (Lipiodol). J Nutr 2001;131(1):72-7.
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  • Kwon EO, Armenakas NA, Scharf SC, Panagopoulos G, Fracchia JA. The poppy seed test for colovesical fistula: big bang, little bucks! J Urol 2008;179(4):1425-7.
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  • Larsson, C., Carlsson, P., and Varenhorst, E. [Poppy seed test helps in the difficult diagnosis of vesico-enteric fistula]. Lakartidningen 9-19-2002;99(38):3703-3705.
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  • Lindequist S, Rasmussen F, Larsen C. Use of iotrolan versus ethiodized poppy-seed oil in hysterosalpingography. Radiology 1994 May;191(2):513-7.
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  • Lindequist S, Justesen P, Larsen C, Rasmussen F. Diagnostic quality and complications of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study. Radiology 1991;179(1):69-74.
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  • Melchior S, Cudovic D, Jones J, Thomas C, Gillitzer R, Thüroff J. Diagnosis and surgical management of colovesical fistulas due to sigmoid diverticulitis. J Urol 2009;182(3):978-82.
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  • Perry, E. K., Pickering, A. T., Wang, W. W., Houghton, P. J., and Perry, N. S. Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy. J Pharm.Pharmacol. 1999;51(5):527-534.
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  • Rasmussen F, Lindequist S, Larsen C, Justesen P. Therapeutic effect of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study. Radiology 1991;179(1):75-8.
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  • Roth, S. L., Dombrowski, H., Hiort, U., Kalbfleisch, H., Ludwig, K., Siefart, F., Seher, A., and Vielhauer, E. [A new contrast medium emulsion for lymphography (author's transl)]. Rofo 1979;131(3):317-321.
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  • Schwaibold H, Popiel C, Geist E, Hartung R. Oral intake of poppy seed: a reliable and simple method for diagnosing vesico-enteric fistula. J Urol 2001;166(2):530-1.
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  • Untoro J, Schultink W, West CE, Gross R, Hautvast JG. Efficacy of oral iodized peanut oil is greater than that of iodized poppy seed oil among Indonesian schoolchildren. Am J Clin Nutr 2006;84(5):1208-14.
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