Background

• Sanicle (Sanicula europaea, Sanicula europa) is a perennial plant in the Apiaceae family that is found in woodlands across Europe, Asia, and Africa. Sanicle products are generally made from the aerial plant parts.
• Sanicle has been used for mild lung inflammation and congestion, cough, and bronchitis. Early study has investigated the potential antifungal, antioxidant, antiviral, and anti-HIV effects of sanicle. Sanicle has also been studied for its use in ear infections, atopic eczema, and asthma.

References

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• Lamaison JL, Petitjean-Freytet C, Carnat A. [Rosmarinic acid, total hydroxycinnamic derivatives and antioxidant activity of Apiaceae, Borraginaceae and Lamiceae medicinals]. Ann Pharm Fr. 1990;48(2):103-108.
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• Matsushita A, Miyase T, Noguchi H, et al. Oleanane saponins from Sanicula elata var. chinensis. J Nat Prod. 2004;67(3):377-383.
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• Schopke T, Janka M, Nimtz M, et al. Saniculoside R-1: a new triterpenoid saponin from Sanicula europaea. Planta Med. 1998;64(1):83-85.
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• Turan K, Nagata K, Kuru A. Antiviral effect of Sanicula europaea L. leaves extract on influenza virus-infected cells. Biochem Biophys Res Commun. 8-5-1996;225(1):22-26.
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• Vargas P, Baldwin BG, Constance L. Nuclear ribosomal DNA evidence for a western North American origin of Hawaiian and South American species of Sanicula (Apiaceae). Proc Natl Acad Sci U.S.A 1-6-1998;95(1):235-240.
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• Viturro C, Molina A, Schmeda-Hirschmann G. Free radical scavengers from Mutisia friesiana (Asteraceae) and Sanicula graveolens (Apiaceae). Phytother Res. 1999;13(5):422-424.
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