Background

• Strontium is a silvery gray element that was first discovered in the early 1800s. It is a soft, easily worked metal that resembles calcium. Because of this similarity, strontium can replace calcium in certain processes in the body. Strontium may promote extra calcium uptake into bones.
• Strontium has sixteen forms: twelve radioactive and four nonradioactive. Strontium-88 is the most common form, making up 83% of natural strontium. Strontium-90 is a radioactive form that earned public attention for being a dangerous byproduct released from nuclear weapons testing in the 1950s. Strontium-89 chloride is another radioactive form used to reduce pain in people with cancer and is the active ingredient in the U.S. Food and Drug Administration (FDA)-approved drug Metastron®.
• In the United States, strontium salts (carbonate, chloride, citrate, gluconate, sulfate, etc.) are available as dietary supplements. According to secondary sources, the most common form of strontium found in dietary supplements is strontium chloride. Strontium chloride, as well as strontium acetate, may be found in dental products like Sensodyne®, a toothpaste used to reduce pain caused by teeth sensitivity.
• In Europe, strontium ranelate is a prescription drug used for osteoporosis. It is marketed under the trade names Protos®, Protelos®, Osseor®, Bivalos®, and Protaxos®. According to previous and ongoing research, strontium ranelate may prevent bone loss, increase bone strength, and reduce fractures in postmenopausal women. It may also benefit people with osteoarthritis.
• Strontium nitrate has been studied for skin irritation and inflammation caused by allergic reactions to cosmetics, personal care products, and drugs, and during occupational exposure. However, large, well-designed trials are needed before a conclusion can be made.
• According to experts, taking calcium and strontium at the same time may reduce strontium absorption. Strontium ranelate should not be used in people with kidney problems. Preliminary studies suggest that strontium may increase the risk of artery blockages.

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